4-Fluoro-3-methoxybenzyl bromide

4-Fluoro-3-methoxybenzyl bromide - Names and Identifiers

Name	4-Fluoro-3-methoxybenzyl bromide
Synonyms	4-fluoro-3-methoxybenzyl choride 3-Methoxy-4-fluorobenzyl bromide 4-Fluoro-3-methoxybenzyl bromide 4-FLUORO-3-METHOXYBENZYL BROMIDE 4-(bromomethyl)-1-fluoro-2-methoxybenzene 4-(BROMOMETHYL)-1-FLUORO-2-METHOXYBENZENE Benzene, 4-(bromomethyl)-1-fluoro-2-methoxy- 4-(Bromomethyl)-1-fluoro-2-methoxybenzene, 5-(Bromomethyl)-2-fluoroanisole, 5-(Bromomethyl)-2-fluorophenyl methyl ether
CAS	141080-73-1
InChI	InChI=1/C8H8BrFO/c1-11-8-4-6(5-9)2-3-7(8)10/h2-4H,5H2,1H3

4-Fluoro-3-methoxybenzyl bromide - Physico-chemical Properties

Molecular Formula	C8H8BrFO
Molar Mass	219.05
Density	1.488
Boling Point	252℃
Flash Point	126℃
Vapor Presure	0.031mmHg at 25°C
Appearance	White solid
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.531
MDL	MFCD04972878

4-Fluoro-3-methoxybenzyl bromide - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

4-Fluoro-3-methoxybenzyl bromide - Introduction

4-fluoro-3-methoxybenzyl bromide (English: 4-Fluoro-3-methoxyphenyl)methyl bromide) is an organic compound. The following is an introduction to some of its properties, uses, formulation and safety information:

1. nature:
4-fluoro-3-methoxybenzyl bromide is a colorless to light yellow liquid with a special aromatic odor. It has a density of about 1.37g/cm³, a boiling point of about 173-174°C, and a flash point of about 104°C. It is poorly soluble in water and soluble in organic solvents such as ether and alcohol solvents.

2. use:
4-fluoro-3-methoxybenzyl bromide has a wide range of applications in the field of organic synthesis. It can be used as an important intermediate for the synthesis of drugs, pesticides and other organic compounds. In the field of medicine, it is often used to synthesize anticancer drugs, antiviral drugs and other bioactive compounds.

3. Preparation method:
The preparation method of 4-fluoro-3-methoxybenzyl bromide usually adopts the method of chemical synthesis. A common method is to obtain 4-fluoro-3-methoxybenzyl alcohol by reacting 3-methoxybenzaldehyde with hydrofluoric acid, and then to obtain the final product by reaction with hydrogen bromide.

4. Safety Information:
When dealing with 4-fluoro-3-methoxybenzyl bromide, the following safety precautions should be paid attention:
-This compound is irritating to the skin, eyes and respiratory tract. Contact with skin and eyes and inhalation of its vapors should be avoided.
-Appropriate personal protective equipment such as gloves, eyes and breathing apparatus should be provided during operation.
-It should be operated in a well-ventilated place to avoid the accumulation of steam in the air.
-When storing and handling, it should be kept separately, away from flammable materials and oxidants.
-When discarding, follow local codes and regulations for proper disposal of residues and effluents.

Last Update：2024-04-09 02:00:42